Frequently Asked Questions

GLP-1 receptor agonists (such as semaglutide and tirzepatide) are medications that mimic the body’s natural glucagon-like peptide-1 hormone. They increase satiety, slow gastric emptying, reduce caloric intake, and improve insulin sensitivity. They are used clinically for both weight management and glycemic control.

Regular follow-up is essential to: Evaluate effectiveness; Adjust dosing; Assess side effects; Support long-term metabolic goals. Follow-up cadence is usually: Monthly while titrating; Every 2–3 months once stable.

When prescribed appropriately and monitored by a physician, GLP-1 medications are considered safe for most adults. Common side effects include: Nausea; Mild GI upset; Decreased appetite; Constipation or diarrhea; Fatigue. Serious adverse events are rare but can include pancreatitis, gallbladder disease, or severe GI intolerance. We screen for risk factors before initiating therapy.

GLP-1s are most effective as part of a long-term metabolic management plan. Stopping them abruptly may result in: Return of appetite; Weight regain; Worsening of underlying metabolic conditions. We focus on sustainable lifestyle changes and dose adjustments to support long-term success.

We do not prescribe GLP-1 therapy for individuals with: Personal or family history of medullary thyroid carcinoma; History of MEN2 syndrome; History of pancreatitis (case by case); Severe GI motility disorders; Active gallbladder disease; Pregnancy or breastfeeding; Known hypersensitivity to GLP-1 agents. Your provider will review your history during the evaluation.

We work with licensed 503A compounding pharmacies that source high-quality APIs and adhere to strict formulation standards. Brand-name prescriptions may be available when clinically appropriate. We do not claim that compounded semaglutide or tirzepatide is FDA-approved.

Baseline labs are recommended in some cases to evaluate: Metabolic markers; A1c; Lipid panels; Renal function; Thyroid function (case dependent). Not all patients require labs before initiation, but they are often helpful in guiding treatment.

We typically prescribe GLP-1 medications for adults who meet at least one of the following: BMI ≥ 30; BMI ≥ 27 with a weight-related condition (prediabetes, hypertension, dyslipidemia, PCOS, sleep apnea, etc.). Patients must also complete a medical intake and be evaluated by a licensed physician before beginning treatment.

Once approved, your prescription is filled by a partner pharmacy and shipped directly to you in temperature-controlled packaging. Typical delivery time: 3–7 business days.

Weight loss occurs through several physiologic mechanisms: Delayed gastric emptying, leading to earlier and prolonged fullness; Reduced appetite via central hypothalamic pathways; Decreased reward-driven eating (reduced craving circuitry); Improved insulin response, reducing post-prandial glucose spikes; Lower overall caloric intake. These changes help patients adopt healthier eating patterns with much less effort than traditional calorie-restriction models.

Most patients experience: Reduced appetite within 1–2 weeks; Noticeable weight loss within 4–6 weeks; Significant weight reduction by 12–16 weeks (dose-dependent). Results vary based on dosing, metabolism, and adherence.

You can message your provider anytime. We commonly adjust: Titration schedule; Dietary recommendations; Hydration strategy; GI management support; Temporary dose pauses when needed. Side effects are usually manageable with guided adjustments.

Most medications are compatible with GLP-1 therapy. Special caution is used with: Insulin; Sulfonylureas; Appetite suppressants; GI motility–affecting medications. We review all medications before prescribing.

Semaglutide: GLP-1 receptor agonist; Excellent appetite suppression; Strong data for weight reduction and glycemic improvement. Tirzepatide: Dual GIP/GLP-1 receptor agonist; Typically produces faster and greater weight loss; May have superior metabolic effects (improved insulin sensitivity, glucose control). Your provider will help you determine which medication aligns with your goals and medical profile.